The following is the detailed research of our Colgate Toothpaste Proof Process.

Colgate Total Anticavity Fluoride and Antigingivitis Advanced Fresh Gel: Active Ingredients: Sodium Fluoride (0.24%) (0.14% W/V Fluoride Ion), Triclosan (0.30%). Inactive Ingredients: Water, Hydrated Silica, Glycerin, Sorbitol, PVM/MA Copolymer, Flavor, Sodium Lauryl Sulfate, Cellulose Gum, Sodium Hydroxide, Propylene Glycol, Carrageenan, Sodium Saccharin, FD&C Blue No. 1, D&C Yellow No. 10

Sodium Fluoride: is produced by neutralizing hydrofluoric acid and hexafluorosilicic acid. Both of these acids are highly corrosive and hydrofluoric is a contact poison as well. Fluoride is toxic when inhaled and ingested, and is lethal at 5–10 g for a 150 lb human. Inhalation causes severe irritation to the respiratory tract. Ingestion may cause salivation, nausea, vomiting, diarrhea, and abdominal pain. Symptoms of weakness, tremors, shallow respiration, carpopedal spasm, convulsions, and coma may follow. Ingestion may cause brain and kidney damage and affect heart and circulatory system. Death may occur from respiratory paralysis. Fluoride skin contact causes irritation, with redness and pain. Eye contact may cause irritation and serious eye damage. Chronic exposure may cause mottling of teeth and bone damage (osteosclerosis) and fluorosis.[1][2]

Triclosan: when combined with chlorine (in some tap water) it can form 2,4- dichlorophenol, which is a carcinogen. 2,4-Dichlorophenol can be fatal because it is easily absorbed through the skin when a liquid.Triclosan is listed as a pesticide and can affects hormone levels.[3][4]

Water: no health or environmental concern.

Hydrated Silica: when inhaled in very small quantities over time can lead to silicosis, bronchitis, or cancer, as it becomes lodged in the lungs and continuously irritates them, reducing lung capacities.[5] Silica dust is labeled as a Group 1- “Carcinogenic to Humans” by the IARC.[6]

Glycerin: no health or enviornmental concern.[7]

Sorbitol: no health or environmental concern.[8]

PVM/MA Copolymer: is a copolymer of methyl vinyl ether and maleic anhydride.[9] Methyl Vinyl Ether when inhaled can cause irritation, headache, dizziness, blurred vision, convulsions; when ingested can cause frostbite, nausea, vomiting, diarrhea; when exposed to skin can cause frostbite; and when exposed to your eye can cause frostbite and blurred vision.[10] Maleic Anhydride when inhaled can cause burning sensation, coughing, sore throat, shortness of breath, wheezing; and when ingested it can cause nausea, abdominal pain, burning sensation, vomiting and diarrhoea. Maleic Anhydride is a respiratory toxicant and strong allergen.[11][12]

Flavor: is a trade secret the exact process and ingredients are unknown.

Sodium Lauryl Sulfate: is a skin irritant that causes corrosion and canker sores. It is also a possible carcinogen.[13][14]

Cellulose Gum: no health or environmental concern.[15]

Sodium Hydroxide (lye): is a corrosive acid that can decompose proteins and lipids in your skin, eyes and tissue which causes chemical burns. It may cause permanent blindness along with severe damage to any tissue it comes in contact with.[16][17]

Propylene Glycol: is produced from propylene oxide, which is labeled as a Group 2B- “Possibly Carcinogenic to Humans” by the IARC.[18] Propylene Glycol is the active component in anti-freeze,[19] and constant and/or excessive contact can lead to increased risk of respiratory and immune disorders like asthma, hay fever, eczema, and allergies.[20][21][22]

Carrageenan: causes inflammation when ingested- chronic inflammation is a root cause of heart disease, Alzheimers, Parkinsons and cancer. Carrageenan is also reported to interfere with macrophage activity.[23][24]

Sodium Saccharin: no enviornmental or health concern.[25]

Blue No 1: produced from petroleum and may be toxic to humans. There is a lack of research related to the health effects of Blue 1.[26]

Yellow No. 10: is considered safe when used in low levels. There is a lack of research related to excessive contact with Yellow 10.[27]


View the Colgate Toothpaste article here.

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